Electrophysiological Identification of Tonic and Phasic Neurons in Sensory Dorsal Root Ganglion and Their Distinct Implications in Inflammatory Pain

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Electrophysiological identification of tonic and phasic neurons in sensory dorsal root ganglion and their distinct implications in inflammatory pain.

In the mammalian autonomic nervous system, tonic and phasic neurons can be differentiated on firing patterns in response to long depolarizing current pulse. However, the similar firing patterns in the somatic primary sensory neurons and their functional significance are not well investigated. Here, we identified two types of neurons innervating somatic sensory in rat dorsal root ganglia (DRG). ...

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The Neuroprotective Effect of Nepeta menthoides on Axotomized Dorsal Root Ganglion Sensory Neurons in Neonate Rats

Background and Objective: Sensory neurons have critical role in improvement of functional outcome of any neuroprotective strategy. The herbal medicine Nepeta menthoides has been reported to have anti-apoptotic effect on axotomized spinal motoneurons. In the present study, the putative neuroprotective effect of Nepeta menthoides on the axotomized dorsal root ganglion sensory neurons in neonate r...

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Morphological Identification of Cell Death in Dorsal Root Ganglion Neurons Following Peripheral Nerve injury and repair in adult rat

Background: Axotomy causes sensory neuronal loss. Reconnection of proximal and distal nerve ends by surgical repair improves neuronal survival. It is important to know the morphology of primary sensory neurons after the surgical repair of their peripheral processes. Methods: Animals (male Wistar rats) were exposed to models of sciatic nerve transection, direct epineurial suture repair of sciati...

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the neuroprotective effect of nepeta menthoides on axotomized dorsal root ganglion sensory neurons in neonate rats

background and objective: sensory neurons have critical role in improvement of functional outcome of any neuroprotective strategy. the herbal medicine nepeta menthoides has been reported to have anti-apoptotic effect on axotomized spinal motoneurons. in the present study, the putative neuroprotective effect of nepeta menthoides on the axotomized dorsal root ganglion sensory neurons in neonate r...

متن کامل

morphological identification of cell death in dorsal root ganglion neurons following peripheral nerve injury and repair in adult rat

background: axotomy causes sensory neuronal loss. reconnection of proximal and distal nerve ends by surgical repair improves neuronal survival. it is important to know the morphology of primary sensory neurons after the surgical repair of their peripheral processes. methods: animals (male wistar rats) were exposed to models of sciatic nerve transection, direct epineurial suture repair of sciati...

متن کامل

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ژورنال

عنوان ژورنال: Physiological Research

سال: 2014

ISSN: 1802-9973,0862-8408

DOI: 10.33549/physiolres.932708